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ISSN : 1225-9306(Print)
ISSN : 2288-0186(Online)
Korean Journal of Medicinal Crop Science Vol.24 No.3 pp.222-227

Antioxidant and α-Glucosidase Inhibitory Activities of Tradescantia pallida (Rose) Hunt Leaf Extract and Fractions

Ju Sung Kim*,**†, Kyeoung Cheol Kim*
*Majors in Plant Resource and Environment, College of Agriculture and Life Sciences, SARI, Jeju National University, Jeju 63243, Korea.
**The Research Institute for Subtropical Agriculture and Biotechnology, Jeju National University, Jeju 63243, Korea.
Corresponding author: (Phone) +82-64-754-3314 (E-mail)


Background: The biological activities of Tradescantia pallida grown in Korea have not been well determined, thus the aim of this study was to investigate the possibility of using it as a medicinal plant.
Methods and Results: To investigate the antioxidant activity, α-glucosidase inhibitory effect and antimicrobial activity of T. pallida, we performed the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity and reducing power assay. This assay for T. pallida leaf extract showed the highest antioxidant activity for the ethyl acetate fraction (RC50= 14.55 ± 0.16㎍/㎖ and Abs = 0.613 at 300㎍). Further, the ethyl acetate fraction exhibited higher α-glucosidase inhibitory effect with an IC50 value of 14.1 ± 0.1㎍/㎖ and showed antimicrobial activity against gram positive bacteria (minimum inhibitory concentration = 1,000㎍/㎖).
Conclusions: The ethyl acetate fraction of the crude methanol extract of T. pallida showed remarkable antioxidant activity, α-glucosidase inhibitory effects and antimicrobial activity. These activities might be related to the flavonoid content in the T. pallida leaf extract.

팔리다자주닭개비 잎 추출물 및 분획물의 항산화 및 α-글루코시다아제 저해 활성

김주성*,**†, 김경철*
*제주대학교 생명자원과학대학 친환경농업연구소, **제주대학교 아열대농업생명과학연구소